Old Mission San Luis Obispo de Tolosa Search | Advanced Search | New Members | Coupons and Discounts | All Categories Religious Organizations >> Churches Old Mission San Luis Obispo de Tolosa 751 Palm St.San Luis Obispo, CA 93401 | map | directions (805) 781-8220 | fax: (805) 781-8214 Visit Site An active Roman Catholic parish, which has been the religious & cultural center of the county since its founding in 1772. Member Since: 2002 Send a message to: Old Mission San Luis Obispo de Tolosa Your Name: Your Email: Subject: Message: (Date: 11/11/2019) If your business isn't here, contact us today to get listed!